Mark Andre studied composition, counterpoint, harmony, and musical analysis at the Conservatoire National Supérieure de Musique de Paris (CNSMP) and composition at the College of Music and Performing Arts in Stuttgart. Among his teachers were Claude Ballif, Gérard Grisey and Helmut Lachenmann. He has been a resident at Villa Medici in Rome (1998–2000) and Fellow of the Berlin Artists’ Program of the DAAD (2005). In 2008 he received the Advancement Award of the Berlin Art Award of the Academy of the Arts. In 2009 the first complete performance of his tryptich …auf…took place in Berlin, and he became a member of the Berlin Academy of the Arts and professor of composition at the Dresden University of Music; in 2010 he was composer-in-residence and lecturer at the 21st Takefu International Music Festival; in 2011 he was awarded the Order Chevalier des Arts et des Lettres by the French Minister of Culture; in 2014 the world premiere of his opera wunderzaichen took place in Stuttgart; and in 2017 he was a lecturer at Impuls in Graz. He lives in Berlin.
 
Mark Andre was a resident at Tarabya Cultural Academy from July 2015 to February 2016.